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Article

Suggestive evidence that Fc variants of IgG2 and FcγRIIa loci interact to contribute to the risk of prostate cancer.

Human immunology - 1 Dec 2013

Pandey Janardan P, Kistner-Griffin Emily, Namboodiri Aryan M, Black Laurel, Jobim Mariana

Abstract excerpt

GM and KM allotypes-hereditary antigenic variants of immunoglobulin γ and κ chains, respectively-and the genetic variants of activating Fcγ receptors (FcγR) are associated with the immunobiology of several malignant diseases, but their role in susceptibility to prostate cancer has not been examined. This investigation aimed to determine whether these genes-individually or in particular epistatic...

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Share to Epistasis, Genetic
Share to Genetic Loci
Share to Immunoglobulin Fc Fragments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin G

Share to Immunoglobulin Gm Allotypes

Share to Neoplasm Grading

Share to Prostatic Neoplasms

Share to Receptors, IgG

Source

Identifiers

PMID: 23994584
DOI: 10.1016/j.humimm.2013.08.280

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