Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin κ C as a Compatible Prognostic Marker in Human Solid Tumors

20 Feb 2012

Abstract excerpt

PURPOSE: Although the central role of the immune system for tumor prognosis is generally accepted, a single robust marker is not yet available. EXPERIMENTAL DESIGN: On the basis of receiver operating characteristic analyses, robust markers were identified from a 60-gene B cell-derived metagene and analyzed in gene expression profiles of 1,810 breast cancer; 1,056 non-small cell lung carcinoma (NSCLC); 513...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Chemokine receptors and signaling
Share to HER2/EGFR in Cancer Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22351685
DOI: 10.1158/1078-0432.ccr-11-2210

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin κ C as a Compatible Prognostic Marker in Human Solid TumorsPMID 22351685Read ↗

Cancer-derived IGKC Suppresses Interferon Signaling and Promotes Tumor MetastasisSemantic proximity Read ↗

Kinome expression profiling and prognosis of basal breast cancersSemantic proximity Read ↗

Conservation of immune gene signatures in solid tumors and prognostic implicationsSemantic proximity Read ↗

High IGKC Expressing Intratumoral Plasma Cells Predict Response to Immune Checkpoint BlockadeSemantic proximity Read ↗

Molecular Profiling of Multiple Human Cancers Defines an Inflammatory Cancer-Associated Molecular Pattern and Uncovers KPNA2 as a Uniform Poor Prognostic Cancer MarkerSemantic proximity Read ↗

BTK is a Prognostic Biomarker for Multiple Human TumorsSemantic proximity Read ↗

The potential of FCRL genes as targets for cancer treatment: insights from bioinformatics and immunology.Semantic proximity Read ↗

IGKC and FcγR genotypes and humoral immunity to HER2 in breast cancer.Semantic proximity Read ↗

Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer.Semantic proximity Read ↗

Prognostic significance of KN motif and ankyrin repeat domains 1 (KANK1) in invasive breast cancerSemantic proximity Read ↗

Inflammatory Breast Cancer: Clinical Implications of Genomic Alterations and Mutational ProfilingSemantic proximity Read ↗

FREM1 Serves as a Novel Therapeutic Target in Breast Cancer through Basement Membrane-Based Prognostic Modeling with Integrated Bioinformatics and Experimental ValidationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.