Article
Determining the cellular diversity of hepatitis C virus quasispecies by single-cell viral sequencing.
Journal of virology - 1 Dec 2013
McWilliam Leitch E Carol, McLauchlan John
Abstract excerpt
Single-cell genomics is emerging as an important tool in cellular biology. We describe for the first time a system to investigate RNA virus quasispecies diversity at the cellular level utilizing hepatitis C virus (HCV) replicons. A high-fidelity nested reverse transcription (RT)-PCR assay was dev...
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