Article
Genome-wide association study of co-occurring anxiety in major depression.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Dec 2013
Schosser Alexandra, Butler Amy W, Uher Rudolf, Ng Mandy Y, Cohen-Woods Sarah, Craddock Nick, Owen Mike J, Korszun Ania, Gill Michael, Rice John, Hauser Joanna, Henigsberg Neven, Maier Wolfgang, Mors Ole, Placentino Anna, Rietschel Marcella, Souery Daniel, Preisig Martin, Craig Ian W, Farmer Anne E, Lewis Cathryn M, McGuffin Peter
Abstract excerpt
OBJECTIVES: Co-morbidity between depression and anxiety disorders is common. In this study we define a quantitative measure of anxiety by summating four anxiety items from the SCAN interview in a large collection of major depression (MDD) cases to identify genes contributing to this complex phenotype. METHODS: A total of 1522 MDD cases dichotomised according to those with at least one anxiety item scored (n =...
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