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Article

Phenotypic distinctions in depression and anxiety: a comparative analysis of comorbid and isolated cases.

Psychological medicine - 1 Dec 2023

Gao Y Nina, Coombes Brandon, Ryu Euijung, Pazdernik Vanessa, Jenkins Gregory, Pendegraft Richard, Biernacka Joanna, Olfson Mark

Abstract excerpt

BACKGROUND: Anxiety and depression are frequently comorbid yet phenotypically distinct. This study identifies differences in the clinically observable phenome across a wide variety of physical and mental disorders comparing patients with diagnoses of depression without anxiety, anxiety without depression, or both depression and anxiety. METHODS: Using electronic health records for 14 994 participants with...

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Identifiers

PMID: 37403468
DOI: 10.1017/S0033291723001745
PMCID: PMC11251006

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