Article
Gender difference in association of NEDD4L gene variants among southern Han Chinese with essential hypertension - a population-based case-control study.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2014
Liang Huiying, Wu Xueji, Chen Xi, Wang Yulin, Li Yaohui, Pan Bingying, Li Ming, Liu Huazhang
Abstract excerpt
Genetic variation of NEDD4L has been associated with hypertension and related phenotypes with conflicting results, probably attributable to gender-, age- and ethnicity-related variations in its phenotypic expression. We evaluated the association of three representative polymorphisms in NEDD4L (rs2288774, rs3865418 and rs4149601) with essential hypertension (EH) in a community-based sample of men (n = 1029) and...
Read the complete abstract on PubMed