Article
A functional variant of NEDD4L is associated with obesity and related phenotypes in a Han population of Southern China.
International journal of molecular sciences - 2 Apr 2013
Wang Yu-Lin, Liang Hui-Ying, Gao Yun-He, Wu Xue-Ji, Chen Xi, Pan Bing-Ying, Yang Xue-Xi, Liu Hua-Zhang
Abstract excerpt
NEDD4L is a candidate gene for hypertension, both functionally and genetically. Recently, studies showed evidence for the association of NEDD4L with obesity, a key intermediate phenotype in hypertension. To further investigate the relationship between NEDD4L and body mass-related phenotypes, we genotyped three common variants (rs2288774, rs3865418 and rs4149601) in a population-based study of 892 unrelated Han...
Read the complete abstract on PubMed