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Article

A Variant in the NEDD4L Gene Associates With Hypertension in Chronic Kidney Disease in the Southeastern Han Chinese Population.

American journal of hypertension - 1 Apr 2020

Zhang Jun, Gong Wen-Yu, Liu Man, Zhou Wenying, Rao Jialing, Li Yuan-Qing, Wu Jian-Hao, Luo Dan, Wang Cheng, Peng Hui

Abstract excerpt

BACKGROUND: "Neuronal precursor cell expressed developmentally down-regulated 4-like" (NEDD4L) is considered a candidate gene for hypertension-both functionally and genetically-through the regulation of the ubiquitination of the epithelial sodium channel (ENaC). This study explores the relationship between genetic variation in NEDD4L and hypertension with chronic kidney disease (CKD) in the southeastern Han...

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Identifiers

PMID: 31993646
DOI: 10.1093/ajh/hpaa015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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