Article
Two polymorphisms in NEDD4L gene and essential hypertension in Chinese Hans - a population-based case-control study.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Feb 2008
Wen Hao, Lin Renyong, Jiao Yi, Wang Fen, Wang Shizhen, Lu Daru, Qian Ji, Jin Li, Wang Xiaofeng
Abstract excerpt
Neural precursor cell expressed developmentally down-regulated 4-like (NEDD4L) gene may play an important role in the development of hypertension by regulating the amiloride-sensitive epithelial sodium channel for sodium reabsorption. Recently, a functional polymorphism located at the last nucleo...
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