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Article

Genetic variation in NEDD4L, an epithelial sodium channel regulator, is associated with cardiovascular disease and cardiovascular death.

Journal of hypertension - 1 Feb 2014

Dahlberg Jonas, Sjögren Marketa, Hedblad Bo, Engström Gunnar, Melander Olle

Abstract excerpt

OBJECTIVES: We have previously shown that genetic variance in NEDD4L, a regulating protein of a sodium channel in the distal nephron, has been associated with marginally higher blood pressure and enhanced salt sensitivity. Here, we tested if the genetic NEDD4L variation previously associated with salt sensitivity is related to population blood pressure, incidence of cardiovascular disease (CVD) and mortality....

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Identifiers

PMID: 24284497
DOI: 10.1097/HJH.0000000000000044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Genetic variation in NEDD4L, an epithelial sodium channel regulator, is associated with cardiovascular disease and cardiovascular death.PMID 24284497Read ↗

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