Article
Association of Ala589Ser polymorphism of WNK4 gene with essential hypertension in a high-risk Chinese population.
The journal of physiological sciences : JPS - 1 Mar 2009
Sun Zhi-Jun, Li Yan, Lu Jing-Yu, Ding Qian, Liang Yu, Shi Jing-Pu, Li-Ling Jesse, Zhao Yan-Yan
Abstract excerpt
Recent studies on the association between particular single nucleotide polymorphisms of serine-threonine kinase with no lysine (K) 4 gene (WNK4) and essential hypertension have yielded controversial results. Here, frequencies of Ala589Ser polymorphism within exon 8 of the WNK4 gene were assessed among 259 unrelated ethnic Chinese patients with essential hypertension and 235 strictly matched normotensive controls....
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