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Article

The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts.

BMC genomics - 17 Sept 2013

Morrison Faer S, Locke Jonathan M, Wood Andrew R, Tuke Marcus, Pasko Dorota, Murray Anna, Frayling Tim, Harries Lorna W

Abstract excerpt

BACKGROUND: Many genetic variants have been associated with susceptibility to complex traits by genome wide association studies (GWAS), but for most, causal genes and mechanisms of action have yet to be elucidated. Using bioinformatics, we identified index and proxy variants associated with autoimmune disease susceptibility, with the potential to affect splicing of candidate genes. PCR and sequence analysis of...

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Identifiers

PMID: 24044605
DOI: 10.1186/1471-2164-14-627
PMCID: PMC3848490

Genes

GSDMB
TSFM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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