Article
Human skin-derived keratinocytes and fibroblasts co-cultured on 3D poly ε-caprolactone scaffold support in vitro HSC differentiation into T-lineage committed cells.
International immunology - 1 Dec 2013
Palamaro Loredana, Guarino Vincenzo, Scalia Giulia, Antonini Dario, De Falco Luigia, Bianchino Gabriella, Fusco Anna, Romano Rosa, Grieco Vitina, Missero Caterina, Del Vecchio Luigi, Ambrosio Luigi, Pignata Claudio
Abstract excerpt
In humans, the thymus is the primary lymphoid organ able to support the development of T cells through its three-dimensional (3D) organization of the thymic stromal cells. Since a remarkable number of similarities are shared between the thymic epithelial cells (TECs) and skin-derived keratinocyte...
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