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The fibroblast: An emerging key player in thymic T cell selection

6 Jun 2021

Abstract excerpt

Fibroblasts have recently attracted attention as a key stromal component that controls the immune responses in lymphoid tissues. The thymus has a unique microenvironment comprised of a variety of stromal cells, including fibroblasts and thymic epithelial cells (TECs), the latter of which is known to be important for T cell development because of their ability to express self-antigens. Thymic fibroblasts...

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PMID: 34096078
DOI: 10.1111/imr.12985

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