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Article

Notch Ligand Presenting Acellular 3D Microenvironments for ex vivo Human Hematopoietic Stem‐Cell Culture made by Layer‐By‐Layer Assembly

30 Mar 2009

Abstract excerpt

Notch ligands presenting artificial 3D thymic microenvironments are created on ICC scaffolds utilizing a layer-by-layer molecular assembly technique (see image). A multicomponent LBL film substitutes the function of thymic stromal cells and successfully supports ex vivo T-cell differentiation of human hematopoietic stem cells.

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Identifiers

PMID: 19334013
DOI: 10.1002/smll.200801242

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