Article
Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens.
Immunology and cell biology - 1 Sept 2015
Skogberg Gabriel, Lundberg Vanja, Berglund Martin, Gudmundsdottir Judith, Telemo Esbjörn, Lindgren Susanne, Ekwall Olov
Abstract excerpt
Exosomes are nano-sized vesicles released by cells into the extracellular space and have been shown to be present in thymic tissue both in mice and in humans. The source of thymic exosomes is however still an enigma and hence it is not known whether thymic epithelial cells (TECs) are able to produce exosomes. In this work, we have cultured human TECs and isolated exosomes. These exosomes carry tissue-restricted...
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