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A Rapid and Scalable Subcutaneously Administered Murine Thymus Micro-organoid for Generating Functional T cells

2025-09-08

Abstract excerpt

Thymic function can decline due to age-related involution, congenital disorders, acute infections, or chemo/radiation therapy. Decline in thymic function leads to decreased T cell production and weakened immunity. To address these thymic insufficiencies, we aimed to develop a transplantable and scalable micro-organoid system utilizing fibroblasts and thymic cells. We have developed a reliable and rapid method to g...

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Literature Corpus work
7adf8f20-b2a3-556e-8e53-5af21b5a0ef5
DOI
10.1101/2025.09.05.671099
Open publication

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A Rapid and Scalable Subcutaneously Administered Murine Thymus Micro-organoid for Generating Functional T cellsDOI 10.1101/2025.09.05.671099
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