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Article

CCR5 deficiency and severe polio infection in the 1984 outbreak in Finland.

Journal of medical virology - 1 Dec 2013

Rosenberg A S, Roivainen M, Hovi T, Liu Q, Murphy P M

Abstract excerpt

CCR5, a leukocyte chemoattractant receptor for chemokines CCL3, CCL4, and CCL5, promotes innate and adaptive immune responses by mediating leukocyte trafficking within lymph nodes and to peripheral tissues and is also known as a co-receptor for HIV cell entry. Homozygous inheritance of a complete loss-of-function mutation in CCR5 (CCR5Δ32/CCR5Δ32) is associated with symptomatic neuroinflammatory disease in humans...

Read the complete abstract on PubMed

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Source

Identifiers

PMID: 24037958
DOI: 10.1002/jmv.23739

Genes

CCR5
CCL3
CCL4
CCL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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