Article
Prevalence of CCR5 Delta 32 Genetic Variant in the Turkmen Population of Golestan Province, Northeast of Iran.
BioMed research international - 1 Jan 2023
Norasi Elmira, Rastegar Mostafa, Hosseini Seyedeh Delafruz, Aghcheli Bahman, Tahamtan Alireza
Abstract excerpt
The 32 bp deletion in the chemokine receptor (C-C motif) 5 gene (CCR5Δ32) is a natural loss of function polymorphism that prevents the protein from locating on the cell surface. This genetic variation acts as a double-edge sword in the pathogenesis/defense mechanism of different health conditions, such as viral infections, autoimmune diseases, and cancers. Here, we evaluated the prevalence of the CCR5Δ32...
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