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Article

Lack of Association Between the CCR5-delta32 Polymorphism and Neurodegenerative Disorders.

Alzheimer disease and associated disorders - 1 Jan 2000

Wojta Kevin J, Ayer Ariane H, Ramos Eliana M, Nguyen Peter D, Karydas Anna M, Yokoyama Jennifer S, Kramer Joel, Lee Suzee E, Boxer Adam, Miller Bruce L, Coppola Giovanni

Abstract excerpt

OBJECTIVE: Recent studies have suggested that diminished Ccr5 functioning has an effect on synaptic plasticity and hippocampal memory in mouse models. CCR5-delta32, a 32-bp frameshift deletion in human CCR5 encoding a nonfunctional receptor, has been reported to have a protective effect against human immunodeficiency virus infection but its role as a modifier of neurodegenerative disease has been minimally...

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Identifiers

PMID: 31972607
DOI: 10.1097/WAD.0000000000000367
PMCID: PMC7365743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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