Article
Assessing the Genomic Landscape of Cervical Cancers: Clinical Opportunities and Therapeutic Targets.
Clinical cancer research : an official journal of the American Association for Cancer Research - 14 Nov 2023
Friedman Claire F, Ravichandran Vignesh, Miller Kathryn, Vanderbilt Chad, Zhou Qin, Iasonos Alexia, Vivek Malavika, Mishra Pamela, Leitao Mario M, Broach Vance, Sonoda Yukio, Kyi Chrisann, Zamarin Dmitriy, O'Cearbhaill Roisin E, Konner Jason, Berger Michael F, Weigelt Britta, Momeni Boroujeni Amir, Park Kay J, Aghajanian Carol, Solit David B, Donoghue Mark T A
Abstract excerpt
PURPOSE: Tumor genomic profiling is increasingly used to guide treatment strategy in patients with cancer. We integrated tumor genomic, clinical demographic, and treatment response data to assess how prospective tumor-normal sequencing impacted treatment selection in patients with cervical cancer. EXPERIMENTAL DESIGN: Cervical cancers were prospectively analyzed using the MSK-IMPACT (Memorial Sloan Kettering...
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