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Article

Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 20 Dec 2006

Prober David A, Rihel Jason, Onah Anthony A, Sung Rou-Jia, Schier Alexander F

Abstract excerpt

As many as 10% of humans suffer chronic sleep disturbances, yet the genetic mechanisms that regulate sleep remain essentially unknown. It is therefore crucial to develop simple and cost-effective vertebrate models to study the genetic regulation of sleep. The best characterized mammalian sleep/wa...

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Identifiers

PMID: 17182791
DOI: 10.1523/JNEUROSCI.4332-06.2006
PMCID: PMC6675014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17182791-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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