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Article

No association between CYP2D6 polymorphisms and personality trait in Japanese.

British journal of clinical pharmacology - 1 Jul 2007

Iwashima Kumiko, Yasui-Furukori Norio, Kaneda Ayako, Saito Manabu, Nakagami Taku, Sato Yasushi, Kaneko Sunao

Abstract excerpt

AIMS: The polymorphic enzyme CYP2D6 is expressed not only in liver but also in brain at low concentrations. CYP2D6 mediates, to some extent, the synthesis of the neurotransmitters, serotonin and dopamine. We investigated a possible association between the genetic polymorphism of CYP2D6 and individual personality trait. METHODS: Mentally and physically healthy volunteers were recruited (n = 342). Temperament and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17324244
DOI: 10.1111/j.1365-2125.2007.02858.x
PMCID: PMC2000607

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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