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Article

Multivariate synaptic and behavioral profiling reveals new developmental endophenotypes in the prefrontal cortex.

Scientific reports - 21 Oct 2016

Iafrati Jillian, Malvache Arnaud, Gonzalez Campo Cecilia, Orejarena M Juliana, Lassalle Olivier, Bouamrane Lamine, Chavis Pascale

Abstract excerpt

The postnatal maturation of the prefrontal cortex (PFC) represents a period of increased vulnerability to risk factors and emergence of neuropsychiatric disorders. To disambiguate the pathophysiological mechanisms contributing to these disorders, we revisited the endophenotype approach from a developmental viewpoint. The extracellular matrix protein reelin which contributes to cellular and network plasticity, is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27765946
DOI: 10.1038/srep35504
PMCID: PMC5073243

Genes

RELN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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