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Article

Mice with Dab1 or Vldlr insufficiency exhibit abnormal neonatal vocalization patterns.

Scientific reports - 17 May 2016

Fraley E R, Burkett Z D, Day N F, Schwartz B A, Phelps P E, White S A

Abstract excerpt

Genetic and epigenetic changes in components of the Reelin-signaling pathway (RELN, DAB1) are associated with autism spectrum disorder (ASD) risk. Social communication deficits are a key component of the ASD diagnostic criteria, but the underlying neurogenetic mechanisms remain unknown. Reln insufficient mice exhibit ASD-like behavioral phenotypes including altered neonatal vocalization patterns. Reelin affects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to LDL-Receptor Related Proteins

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Source

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Identifiers

PMID: 27184477
DOI: 10.1038/srep25807
PMCID: PMC4868998

Genes

DAB1
RELN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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