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Article

YY1 binds to α-synuclein 3'-flanking region SNP and stimulates antisense noncoding RNA expression.

Journal of human genetics - 1 Nov 2013

Mizuta Ikuko, Takafuji Kazuaki, Ando Yuko, Satake Wataru, Kanagawa Motoi, Kobayashi Kazuhiro, Nagamori Shushi, Shinohara Takayuki, Ito Chiyomi, Yamamoto Mitsutoshi, Hattori Nobutaka, Murata Miho, Kanai Yoshikatsu, Murayama Shigeo, Nakagawa Masanori, Toda Tatsushi

Abstract excerpt

α-synuclein (SNCA) is an established susceptibility gene for Parkinson's disease (PD), one of the most common human neurodegenerative disorders. Increased SNCA is considered to lead to PD and dementia with Lewy bodies. Four single-nucleotide polymorphisms (SNPs) in SNCA 3' region were prominently associated with PD among different ethnic groups. To examine how these SNPs influence disease susceptibility, we...

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Identifiers

PMID: 24026176
DOI: 10.1038/jhg.2013.90

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SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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YY1 binds to α-synuclein 3'-flanking region SNP and stimulates antisense noncoding RNA expression.PMID 24026176Read ↗

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