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Article

SNCA 3' UTR Genetic Variants in Patients with Parkinson's Disease.

Biomolecules - 30 Nov 2021

Blažeković Antonela, Jerčić Kristina Gotovac, Borovečki Fran

Abstract excerpt

The SNCA (Synuclein Alpha) gene represents a major risk gene for Parkinson's disease (PD) and SNCA polymorphisms have been associated with the common sporadic form of PD. Numerous Genome-Wide Association Studies showed strong signals located in the SNCA 3' UTR (untranslated region) region indicating that variants in 3' UTRs of PD-associated genes could contribute to neurodegeneration and may regulate the risk for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34944443
DOI: 10.3390/biom11121799
PMCID: PMC8698872

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