Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcripts

1 Nov 2023

Abstract excerpt

Alpha-synuclein (SNCA) accumulation plays a central role in the pathogenesis of Parkinson's disease. Determining and interfering with the mechanisms that control SNCA expression is one approach to limiting disease progression. Currently, most of our understanding of SNCA regulation is protein-based. Post-transcriptional mechanisms directly regulating SNCA mRNA expression via its 3′ untranslated region (3′UTR)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA regulation and disease
Share to RNA Research and Splicing
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37989221
DOI: 10.1098/rsob.230158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcriptsPMID 37989221Read ↗

hnRNPA1 orchestrates multi-layered regulation of SNCA expressionSemantic proximity Read ↗

A Comprehensive Analysis of the Role of hnRNP A1 Function and Dysfunction in the Pathogenesis of Neurodegenerative DiseaseSemantic proximity Read ↗

hnRNP A1: The Swiss Army Knife of Gene ExpressionSemantic proximity Read ↗

Discovering the 3' UTR-mediated regulation of alpha-synuclein.Semantic proximity Read ↗

The Roles of hnRNP Family in the Brain and Brain-Related DisordersSemantic proximity Read ↗

Neuronal RNA ‐binding proteins in health and diseaseSemantic proximity Read ↗

Unraveling the Pathways to Neuronal Homeostasis and Disease: Mechanistic Insights into the Role of RNA-Binding Proteins and Associated FactorsSemantic proximity Read ↗

Alpha-synuclein abundance and localization are regulated by the RNA-binding protein PUMILIO1Semantic proximity Read ↗

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s diseaseSemantic proximity Read ↗

RNA-binding proteins in neurological diseases.Semantic proximity Read ↗

The hnRNP family: insights into their role in health and diseaseSemantic proximity Read ↗

Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.