A search for SNCA 3' UTR variants identified SNP rs356165 as a determinant of disease risk and onset age in Parkinson's disease.

doi:10.1007/s12031-011-9669-1

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Article

A search for SNCA 3' UTR variants identified SNP rs356165 as a determinant of disease risk and onset age in Parkinson's disease.

Journal of molecular neuroscience : MN - 1 Jul 2012

Cardo Lucía F, Coto Eliecer, de Mena Lorena, Ribacoba René, Lorenzo-Betancor Oswaldo, Pastor Pau, Samaranch Lluis, Mata Ignacio F, Díaz Marta, Moris Germán, Menéndez Manuel, Corao Ana I, Alvarez Victoria

Abstract excerpt

Alpha-synuclein gene (SNCA) polymorphisms have been associated with the common sporadic form of Parkinson's disease (PD). We searched for DNA variants at the SNCA 3' UTR through single strand conformation analysis and direct sequencing in a cohort of Spanish PD patients and controls. We have genotyped the rs356165 SNCA 3' UTR polymorphism in a total of 1,135 PD patients and 772 healthy controls from two Spanish...

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PMID: 22076805
DOI: 10.1007/s12031-011-9669-1

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SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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