Article
Association study of the vesicular monoamine transporter gene SLC18A2 with tardive dyskinesia.
Journal of psychiatric research - 1 Nov 2013
Zai Clement C, Tiwari Arun K, Mazzoco Marina, de Luca Vincenzo, Müller Daniel J, Shaikh Sajid A, Lohoff Falk W, Freeman Natalie, Voineskos Aristotle N, Potkin Steven G, Lieberman Jeffrey A, Meltzer Herbert Y, Remington Gary, Kennedy James L
Abstract excerpt
Tardive dyskinesia (TD) is an involuntary movement disorder that can occur in up to 25% of patients receiving long-term first-generation antipsychotic treatment. Its etiology is unclear, but family studies suggest that genetic factors play an important role in contributing to risk for TD. The vesicular monoamine transporter 2 (VMAT2) is an interesting candidate for genetic studies of TD because it regulates the...
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