Article
New insights into tardive dyskinesia genetics: Implementation of whole-exome sequencing approach.
Progress in neuro-psychopharmacology & biological psychiatry - 30 Aug 2019
Alkelai Anna, Greenbaum Lior, Heinzen Erin L, Baugh Evan H, Teitelbaum Alexander, Zhu Xiaolin, Strous Rael D, Tatarskyy Pavel, Zai Clement C, Tiwari Arun K, Tampakeras Maria, Freeman Natalie, Müller Daniel J, Voineskos Aristotle N, Lieberman Jeffrey A, Delaney Shannon L, Meltzer Herbert Y, Remington Gary, Kennedy James L, Pulver Ann E, Peabody Emma P, Levy Deborah L, Lerer Bernard
Abstract excerpt
Tardive dyskinesia (TD) is an adverse movement disorder induced by chronic treatment with antipsychotics drugs. The contribution of common genetic variants to TD susceptibility has been investigated in recent years, but with limited success. The aim of the current study was to investigate the potential contribution of rare variants to TD vulnerability. In order to identify TD risk genes, we performed whole-exome...
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