Article
Glial cell line-derived neurotrophic factor receptor alpha 2 (GFRA2) gene is associated with tardive dyskinesia.
Psychopharmacology - 1 Jun 2010
Souza Renan P, de Luca Vincenzo, Remington Gary, Lieberman Jeffrey A, Meltzer Herbert Y, Kennedy James L, Wong Albert H C
Abstract excerpt
INTRODUCTION: Tardive dyskinesia (TD) has a pharmacogenetic component in which the interaction of antipsychotic exposure with individual genetic variation mediates risk. The glial cell line-derived neurotrophic factor (GDNF) signalling pathway has been associated with neuroprotective effects in c...
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