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Article

Analysis of genetic variations in the dopamine D1 receptor (DRD1) gene and antipsychotics-induced tardive dyskinesia in schizophrenia.

European journal of clinical pharmacology - 1 Apr 2011

Lai I-Ching, Mo Geng-Han, Chen Mao-Liang, Wang Ying-Chieh, Chen Jen-Yeu, Liao Ding-Lieh, Bai Ya-Mei, Lin Chao-Cheng, Chen Tzu-Ting, Liou Ying-Jay

Abstract excerpt

BACKGROUND: Dyskinesia is a kind of abnormal involuntary movement disorder that increases with age. The pathogenesis of dyskinesia may result from divergent changes in dopamine D1 receptors (DRD1) and dopamine D2 receptors (DRD2) in the brain while aging. Tardive dyskinesia (TD), a kind of dyskinesia, may develop after long-term antipsychotic treatment. Because the prevalence of TD also steadily increased with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21181138
DOI: 10.1007/s00228-010-0967-2

Genes

DRD1
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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