Article
Genetic susceptibility to Tardive Dyskinesia in chronic schizophrenia subjects: V. Association of CYP1A2 1545 C>T polymorphism.
The pharmacogenomics journal - 1 Oct 2007
Tiwari A K, Deshpande S N, Lerer B, Nimgaonkar V L, Thelma B K
Abstract excerpt
Tardive dyskinesia (TD) is an iatrogenic disorder observed in approximately 20-30% of schizophrenia patients on long-term treatment with typical antipsychotic drugs. CYP1A2 is involved in the metabolism of atypical antipsychotic drugs such as clozapine and olanzapine. It is not directly involved...
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