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Article

Autonomous functions of murine thyroid hormone receptor TRα and TRβ in cochlear hair cells.

Molecular and cellular endocrinology - 25 Jan 2014

Dettling Juliane, Franz Christoph, Zimmermann Ulrike, Lee Sze Chim, Bress Andreas, Brandt Niels, Feil Robert, Pfister Markus, Engel Jutta, Flamant Frédéric, Rüttiger Lukas, Knipper Marlies

Abstract excerpt

Thyroid hormone acts on gene transcription by binding to its nuclear receptors TRα1 and TRβ. Whereas global deletion of TRβ causes deafness, global TRα-deficient mice have normal hearing thresholds. Since the individual roles of the two receptors in cochlear hair cells are still unclear, we gener...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to KCNQ Potassium Channels

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Share to Otoacoustic Emissions, Spontaneous

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Source

Identifiers

PMID: 24012852
DOI: 10.1016/j.mce.2013.08.025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24012852-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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