Article
Effects of the lethal yellow (Ay) mutation in mouse aggregation chimeras.
Development (Cambridge, England) - 1 Jul 1990
Barsh G S, Lovett M, Epstein C J
Abstract excerpt
The Ay allele is a recessive lethal mutation at the mouse agouti locus, which results in embryonic death around the time of implantation. In the heterozygous state, Ay produces several dominant pleiotropic effects, including an increase in weight gain and body length, a susceptibility to hepatic,...
Topics
- Animals
- Body Weight
- Chimera
- Genes, Lethal
- Genotype
- Mice
- Mice, Inbred Strains
- Mutation
- Obesity