Article
Prenatal determination of obesity, tumor susceptibility, and coat color pattern in viable yellow (Avy/a) mice. The yellow mouse syndrome.
The Journal of heredity - 1 Jan 2000
Wolff G L, Roberts D W, Galbraith D B
Abstract excerpt
Maturity-onset obesity and elevated circulating insulin levels are characteristic of some, but not all, mice bearing the viable yellow mutation (Avy) at the agouti locus. The expression of the Avy/a genotype in individual mice, which become obese and which remain lean is determined during prenatal development by as yet unidentified conditions in the dam's reproductive tract. One Avy/a phenotype is identified by a...
Topics
- Animals
- Disease Susceptibility
- Embryonic and Fetal Development
- Female
- Hair Color
- Mice
- Mice, Mutant Strains
- Mutation
- Neoplasms, Experimental
- Obesity
- Phenotype