Article
The eye photoreceptor protein rhodopsin. Structural implications for retinal disease.
FEBS letters - 25 Sept 2002
Garriga Pere, Manyosa Joan
Abstract excerpt
Rhodopsin is the membrane receptor responsible for photoreception in the vertebrate retina. Its characteristic seven-transmembrane helical structural motif is today widely recognised as a paradigm in signal transduction. Rhodopsin and the phototransduction system are frequently used as structural and mechanistic models for the G-protein coupled receptor superfamily. Recent advances in the activation mechanism (as...
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