Rhodopsin mutations as the cause of retinal degeneration. Classification of degeneration phenotypes in the model system Drosophila melanogaster.

Abstract excerpt

Insight into the molecular basis of inherited photoreceptor cell degeneration has been rapidly evolving during the last decade. The Drosophila Rh1 rhodopsin gene was the first gene shown to cause retinal degeneration when mutated. Many more degeneration-causing mutations in genes encoding rhodops...

Topics

• Amino Acid Sequence
• Animals
• Disease Models, Animal
• Drosophila melanogaster
• Genotype
• Molecular Sequence Data
• Phenotype
• Photoreceptor Cells, Invertebrate
• Point Mutation
• Retinal Degeneration
• Rhodopsin