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Article

Rhodopsin as a Molecular Target to Mitigate Retinitis Pigmentosa.

Advances in experimental medicine and biology - 1 Jan 2022

Ortega Joseph T, Jastrzebska Beata

Abstract excerpt

Retinitis pigmentosa (RP) is a group of hereditary degenerative diseases affecting 1 of 4000 people worldwide and being the most prevalent cause of visual handicap among working populations in developed countries. These disorders are mainly related to the abnormalities in the rod G protein-coupled receptor (GPCR), rhodopsin reflected in the dysregulated membrane trafficking, stability and phototransduction...

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Identifiers

PMID: 34962636
DOI: 10.1007/5584_2021_682

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