Article
A Fluorescence-Based Genetic Screen to Study Retinal Degeneration in Drosophila.
PloS one - 1 Jan 2015
Huang Yu, Xie Jun, Wang Tao
Abstract excerpt
The Drosophila visual system has been proved to be a powerful genetic model to study eye disease such as retinal degeneration. Here, we describe a genetic method termed "Rh1::GFP ey-flp/hid" that is based on the fluorescence of GFP-tagged major rhodopsin Rh1 in the eyes of living flies and can be used to monitor the integrity of photoreceptor cells. Through combination of this method and ERG recording, we...
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