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Article

c‐Ski activates cancer‐associated fibroblasts to regulate breast cancer cell invasion

27 Aug 2013

Abstract excerpt

Aberrant expression of c-Ski oncoprotein in some tumor cells has been shown to be associated with cancer development. However, the role of c-Ski in cancer-associated fibroblasts (CAFs) of tumor microenvironment has not been characterized. In the current study, we found that c-Ski is highly expressed in CAFs derived from breast carcinoma microenvironment and this CAF-associated c-Ski expression is associated with...

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PMID: 24011664
DOI: 10.1016/j.molonc.2013.08.007

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