Back to search

Article

MiR-3613-3p from carcinoma associated fibroblasts exosomes promoted breast cancer cell proliferation and metastasis by regulating SOCS2 expression

2020-02-27

Abstract excerpt

<h4>Background: </h4> Exosomes carrying microRNA (miRNAs) mediate cell to cell communication which are important regulators in cancer growth and progression. However, the roles and molecular mechanism of the miRNAs in the exosomes from carcinoma associated fibroblasts (CAFs) are still not clear. Methods The targeted gene of miR-3613-3p was predicted by TargetScan and miRanda. The proliferation of cancer cells was...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d85c56f2-c9eb-5cf9-9528-d45f39a043b7
DOI
10.21203/rs.2.24682/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
MiR-3613-3p from carcinoma associated fibroblasts exosomes promoted breast cancer cell proliferation and metastasis by regulating SOCS2 expressionDOI 10.21203/rs.2.24682/v1
Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer.Semantic proximity
Cancer-associated fibroblasts-derived exosomes suppresses immune cell function in breast cancer via miR-92/PD-L1 pathwaySemantic proximity
Shining the light on mesenchymal stem cell-derived exosomes in breast cancerSemantic proximity
Exosomes derived from cancer-associated fibroblasts promote tumorigenesis, metastasis, chemoresistance of colorectal cancer cells by upregulating circ_0067557 to target Lin28A and Lin28BSemantic proximity
Evaluation of MiR-1908-3p as a novel serum biomarker for breast cancer and analysis its oncogenic function and target genesSemantic proximity
Analysis of mRNA-miRNA interaction network reveals the role of CAFs-derived exosomes in the immune regulation of oral squamous cell carcinomaSemantic proximity
THAP7-AS1 recruits the SWI/SNF to activate EGFR-ELK1 signaling and induce crosstalk between tumor-associated macrophages and breast cancer cellsSemantic proximity
Exosomes deep sequencing identifies miR-363-5p as a non-invasive biomarker of axillary lymph node metastasis and prognosis in breast cancerSemantic proximity
Exosomal miR-93-5p from cancer-associated fibroblasts confers malignant phenotypes on bladder cancer cells by targeting PAFAH1B1.Semantic proximity
Hierarchical paracrine interaction of breast cancer associated fibroblasts with cancer cells via hMAPK-microRNAs to drive ER-negative breast cancer phenotype.Semantic proximity
Hypoxic cancer-associated fibroblast exosomal circSTAT3 drives triple negative breast cancer stemness via miR-671-5p/NOTCH1 signalingSemantic proximity
The inhibition of circular RNA circNOLC1 by propofol/STAT3 attenuates breast cancer stem cells function via miR-365a-3p/STAT3 signalingSemantic proximity
Select a neighboring publication to make it the new centre.