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Article

c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion.

The Journal of biological chemistry - 12 Mar 2010

Jiao Xuanmao, Katiyar Sanjay, Willmarth Nicole E, Liu Manran, Ma Xiaojing, Flomenberg Neal, Lisanti Michael P, Pestell Richard G

Abstract excerpt

The molecular mechanisms governing breast tumor cellular self-renewal contribute to breast cancer progression and therapeutic resistance. The ErbB2 oncogene is overexpressed in approximately 30% of human breast cancers. c-Jun, the first cellular proto-oncogene, is overexpressed in human breast ca...

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Source

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Identifiers

PMID: 20053993
DOI: 10.1074/jbc.M110.100792
PMCID: PMC2832973

Genes

CCL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20053993-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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