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Article

Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes.

Pain - 1 Dec 2013

Bruehl Stephen, Denton Jerod S, Lonergan Daniel, Koran Mary Ellen, Chont Melissa, Sobey Christopher, Fernando Shanik, Bush William S, Mishra Puneet, Thornton-Wells Tricia A

Abstract excerpt

G-protein coupled inwardly rectifying potassium (GIRK) channels are effectors determining degree of analgesia experienced upon opioid receptor activation by endogenous and exogenous opioids. The impact of GIRK-related genetic variation on human pain responses has received little research attentio...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23994450
DOI: 10.1016/j.pain.2013.08.026
PMCID: PMC3845348

Genes

KCNJ6
KCNJ3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23994450-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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