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Article

Association between KCNJ6 (GIRK2) gene polymorphism rs2835859 and post-operative analgesia, pain sensitivity, and nicotine dependence.

Journal of pharmacological sciences - 1 Jan 2014

Nishizawa Daisuke, Fukuda Ken-ichi, Kasai Shinya, Ogai Yasukazu, Hasegawa Junko, Sato Naomi, Yamada Hidetaka, Tanioka Fumihiko, Sugimura Haruhiko, Hayashida Masakazu, Ikeda Kazutaka

Abstract excerpt

G-protein-activated inwardly rectifying potassium (GIRK) channels are expressed in many tissues and activated by several Gi/o protein-coupled receptors, such as opioid and dopamine receptors, and thus are known to be involved in the modulation of opioid-induced analgesia, pain, and reward. We focused on a GIRK-channel subunit that plays a pivotal role in the brain, GIRK2, and investigated the contribution of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25346042
DOI: 10.1254/jphs.14189fp

Genes

KCNJ6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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