Article
Association between KCNJ6 (GIRK2) gene polymorphisms and postoperative analgesic requirements after major abdominal surgery.
PloS one - 16 Sept 2009
Nishizawa Daisuke, Nagashima Makoto, Katoh Ryoji, Satoh Yasuo, Tagami Megumi, Kasai Shinya, Ogai Yasukazu, Han Wenhua, Hasegawa Junko, Shimoyama Naohito, Sora Ichiro, Hayashida Masakazu, Ikeda Kazutaka
Abstract excerpt
Opioids are commonly used as effective analgesics for the treatment of acute and chronic pain. However, considerable individual differences have been widely observed in sensitivity to opioid analgesics. We focused on a G-protein-activated inwardly rectifying potassium (GIRK) channel subunit, GIRK...
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