Article
A machine-learned knowledge discovery method for associating complex phenotypes with complex genotypes. Application to pain.
Journal of biomedical informatics - 1 Oct 2013
Lötsch Jörn, Ultsch Alfred
Abstract excerpt
BACKGROUND: The association of genotyping information with common traits is not satisfactorily solved. One of the most complex traits is pain and association studies have failed so far to provide reproducible predictions of pain phenotypes from genotypes in the general population despite a well-established genetic basis of pain. We therefore aimed at developing a method able to prospectively and highly accurately...
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