Article
Isocitrate dehydrogenase 1 (IDH1) mutation-specific microRNA signature predicts favorable prognosis in glioblastoma patients with IDH1 wild type.
Journal of experimental & clinical cancer research : CR - 29 Aug 2013
Wang Zheng, Bao Zhaoshi, Yan Wei, You Gan, Wang Yinyan, Li Xuejun, Zhang Wei
Abstract excerpt
BACKGROUND: To date, no prognostic microRNAs (miRNAs) for isocitrate dehydrogenase 1 (IDH1) wild-type glioblastoma multiformes (GBM) have been reported. The aim of the present study was to identify a miRNA signature of prognostic value for IDH1 wild-type GBM patients using miRNA expression dataset from the The Cancer Genome Atlas (TCGA). METHODS: Differential expression profiling analysis of miRNAs was performed...
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