Article
The potential implication of SCN1A and CYP3A5 genetic variants on antiepileptic drug resistance among Egyptian epileptic children.
Seizure - 1 Oct 2016
Abo El Fotoh Wafaa Moustafa M, Abd El Naby Sameh Abd Allah, Habib Mona Salah El-Din, ALrefai Abeer Ahmed, Kasemy Zeinab A
Abstract excerpt
PURPOSE: Despite the advances in the pharmacological treatment of epilepsy, pharmacoresistance still remains challenging. Understanding of the pharmacogenetic causes is critical to predict drug response hence providing a basis for personalized medications. Genetic alteration in activity of drug target and drug metabolizing proteins could explain the development of pharmacoresistant epilepsy. So the aim of this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.